The Evidence

The research on ketamine for mental health is rapidly expanding and evolving. Everyone is talking about it! Included here are a mix of scientific studies, articles, and videos from the popular media, and professional articles. We try to keep this page fresh! This is just a sample of what is out there about ketamine, it is important to do your own research. We are happy to discuss any information you bring to us about ketamine and answer your questions.

The name “Bloom” is inspired by the results of research done by Yale and the National Institute of Health that say ketamine causes a burst of new connections to form between nerve cells in parts of the brain involved in emotion and mood. This process is called synaptogenesis.

This “before and after” image of the nerve endings of a rat brain used in the study shows the research results. This image is the inspiration for the name Bloom. The study’s results were the inspiration for offering ketamine to Winona and surrounding communities.

Ketamine is a chance to push the reset button on your mental health and participate more fully in the actions we can all take to feel better and grow.

Popular Media Articles

Local Photographer Discusses Mental Health in Current Exhibit – Winona Post 2020
http://www.winonapost.com/Article/ArticleID/67734/Sharing-mental-health-stories

Prying open the Third Eye – Boulder news 2017 article
https://www.boulderweekly.com/news/prying-open-third-eye/

New Nasal Ketamine; What’s Different from IV Ketamine? – The Verge 2019 article
https://www.theverge.com/2019/3/11/18260297/esketamine-fda-approval-depression-ketamine-clinic-science-health

Ketamine appears to restore brain connections – NPR 2012 article
https://www.npr.org/sections/health-shots/2012/10/04/162299564/ketamine-relieves-depression-by-restoring-brain-connections

Can Ketamine treat depression? – The Doctors 2019 Video
https://www.thedoctorstv.com/videos/can-depression-be-treated-ketamine

Experience Ketamine – Tonic 2017 video – (please watch this in its entirety)
https://youtu.be/PAfLnXFIENk

Booze, Obesity and Depression in Winona County – Winona Post 2019 article
http://www.winonapost.com/Archives/ArticleID/65356/Booze-obesity-and-depression-in-Winona-Co

Is Ketamine the New Wonder Drug?
https://www.fieldtriphealth.com/blog/is-ketamine-the-new-wonder-drug

Professional Articles

Dissociation during Ketamine infusion- does it matter? – Lori Calabrese, MD 2018
https://loricalabresemd.com/blog/dissociation-is-it-the-key-to-ketamines-antidepressant-response/

Ketamine; Features of dissociation Study – Journal of Affective Disorders 2018
https://www.sciencedirect.com/science/article/abs/pii/S0165032717324783

Ketamine treats Major Depression: Harvard Health Journal 2019 article
https://www.health.harvard.edu/blog/ketamine-for-major-depression-new-tool-new-questions-2019052216673

Ketamine offers hope to Vets with depression: Psychology Today 2019 article
http://www.psychologytoday.com/us/blog/ketamine-new-way-treat-teen-depression/201909/ketamine-offers-hope-vets-struggling-depression

Ketamine raises neuroplasticity in the nervous system – Scientific American 2019
https://www.scientificamerican.com/article/behind-the-buzz-how-ketamine-changes-the-depressed-patients-brain/

Listening to Ketamine (a very comprehensive article) – Knowable magazine 2019
https://www.knowablemagazine.org/article/mind/2019/listening-ketamine

The Concept of Booster Infusions – Klarisana 2017 video
https://youtu.be/hIq5gtSSx68

VA uses ketamine to treat PTSD effectively
https://www.pharmacist.com/article/va-uses-ketamine-treat-ptsd-effectively

Ketamine: A Promising Novel Therapy for Anxiety and PTSD
https://www.psychiatryadvisor.com/home/topics/anxiety/ketamine-a-promising-novel-therapy-for-anxiety-and-ptsd/

Researchers pinpoint brain circuitry underlying dissociative experiences | News Center
https://med.stanford.edu/news/all-news/2020/09/researchers-pinpoint-brain-circuitry-underlying-dissociation.html

Scientists Discover How Drugs Like Ketamine Induce An Altered State Of Mind : Shots – Health News
https://www.npr.org/sections/health-shots/2020/09/16/913565163/scientists-discover-way-to-induce-altered-state-of-mind-without-drugs

Scientific Research

Presentation of Research at Yale – Yale Univ 2012 Video
https://www.youtube.com/watch?v=hNsIiq-5354

Ketamine; Features of dissociation Study – Journal of Affective Disorders 2018
https://www.sciencedirect.com/science/article/abs/pii/S0165032717324783

2013 Study results: Antidepressant Effectiveness of Ketamine – Am Journal of Psychiatry article
https://www.ncbi.nlm.nih.gov/pubmed/23982301

2015 Study results: Ketamine for Rapid Reduction of Suicidal Ideation – Psychol Med
https://pubmed.ncbi.nlm.nih.gov/26266877/

NIMH » Ketamine Lifts Depression via a Byproduct of its Metabolism
https://www.nimh.nih.gov/news/science-news/2016/ketamine-lifts-depression-via-a-byproduct-of-its-metabolism.shtml

Ketamine for Depression: Where Do We Go from Here? (Biological Psychiatry)
https://www.sciencedirect.com/science/article/abs/pii/S0006322312004179

Dissociative and Analgesic Properties of Ketamine Are Independent | Anesthesiology (Nov. 2020)
https://pubs.asahq.org/anesthesiology/article/133/5/1021/110471/Dissociative-and-Analgesic-Properties-of-Ketamine

Ketamine can reduce harmful drinking by pharmacologically rewriting drinking memories
https://www.nature.com/articles/s41467-019-13162-w

Remission from Chronic Anorexia Nervosa With Ketogenic Diet and Ketamine: Case Report
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7412264/

The effects of ketamine on suicidality across various formulations and study settings
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6322816/

Titrated Serial Ketamine Infusions Stop Outpatient Suicidality and Avert ER Visits and Hospitalizations — PDF download
https://www.scivisionpub.com/pdfs/titrated-serial-ketamine-infusions-stop-outpatient-suicidality-and-avert-er-visits-and-hospitalizations-918.pdf

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We reply to all emails and form submissions. If you don’t receive a reply within 24 hours of your inquiry, please check your junk/spam mail folder and/or call the office.

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902 E 2nd St. Suite 325
Winona MN 55987

507-494-8702